PXD020913

PXD020913 is an original dataset announced via ProteomeXchange.

Title	An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer
Description	The role of different cells in the tumor microenvironment (TME) is critical to the metastatic process. Phenotypic transformation of the liver cells is one of the most important stages of hepatic metastasis progression of colorectal cancer (CRC). Our aim was to identify the major molecules (i.e. genes, miRNAs and proteins) involved in this process.
HostingRepository	PRIDE
AnnounceDate	2020-08-27
AnnouncementXML	Submission_2020-08-27_08:47:13.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Gereon Poschmann
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Elite

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-14 07:32:44	ID requested
⏵ 1	2020-08-27 08:47:15	announced

Gerovska D, Larrinaga G, Solano-Iturri JD, M, á, rquez J, Garc, í, a Gallastegi P, Khatib AM, Poschmann G, St, ü, hler K, Armesto M, Lawrie CH, Badiola I, Ara, ú, zo-Bravo MJ, in Hepatic Metastatic Progression of Colorectal Cancer. Cancers (Basel), 12(9):(2020) [pubmed]

Marquez J, Fernandez-Pi, ñ, eiro I, Ara, ú, zo-Bravo MJ, Poschmann G, St, ü, hler K, Khatib AM, Sanchez A, Unda F, Ibarretxe G, Bernales I, Badiola I, Targeting liver sinusoidal endothelial cells with miR-20a-loaded nanoparticles reduces murine colon cancer metastasis to the liver. Int J Cancer, 143(3):709-719(2018) [pubmed]

submitter keyword: Colorectal cancer, tumor microenvironment, BRCA1, metastasis

Gereon Poschmann
contact affiliation	Proteome Research (AG Stühler) Institute of Molecular Medicine I Heinrich Heine University Düsseldorf Universitätsstraße 1 40225 Düsseldorf
contact email	gereon.poschmann@hhu.de
lab head
Gereon Poschmann
contact affiliation	Molecular Proteomics Laboratory
contact email	gereon.poschmann@hhu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD020913

PRIDE project URI

• PRIDE
  1. PXD020913
     1. Label: PRIDE project
     2. Name: An Integrative Omics Approach Reveals Involvement of BRCA1 in Hepatic Metastatic Progression of Colorectal Cancer