PXD020903

PXD020903 is an original dataset announced via ProteomeXchange.

Title	Alteration of protein expression and spliceosome pathway activity during Barrett’s carcinogenesis.
Description	Esophageal adenocarcinoma (EAC) is a common and aggressive type of cancer and Barrett’s esophagus (BE) is a known precursor lesion and the strongest risk factor for EAC. Prediction of risk is currently based on histologic examination which is challenged by problems such as inter-observer variability due to high heterogeneity of the dysplastic tissue. Molecular markers might offer an additional way to understand carcinogenesis and improve diagnosis and eventually treatment. .
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_04:17:32.734.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020903
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Christoph Stingl
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-13 22:49:26	ID requested
⏵ 1	2021-09-09 04:17:33	announced

Stingl C, Bureo Gonzalez A, G, ü, zel C, Phoa KYN, Doukas M, Breimer GE, Meijer SL, Bergman JJ, Luider TM, Alteration of protein expression and spliceosome pathway activity during Barrett's carcinogenesis. J Gastroenterol, 56(9):791-807(2021) [pubmed]

submitter keyword: Barrett’s esophagus, dysplastia, adenocarcinoma, epithelial cells, laser capture micro-dissection, bottom-up proteomics, mass spectrometry

Theo M. Luider
contact affiliation	ErasmusMC, Dept. of Neurology, Laboratory Clinical & Cancer Proteomics, Rotterdam, The Netherlands
contact email	t.luider@erasmusmc.nl
lab head
Christoph Stingl
contact affiliation	Erasmus MC Rotterdam Department of Neurology
contact email	c.stingl@erasmusmc.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020903

PRIDE project URI

• PRIDE
  1. PXD020903
     1. Label: PRIDE project
     2. Name: Alteration of protein expression and spliceosome pathway activity during Barrett’s carcinogenesis.