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PXD020852

PXD020852 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe calcium-permeable channel OSCA1.3 regulates plant stomatal immunity
DescriptionPerception of biotic and abiotic stresses often leads to stomatal closure in plants. Rapid influx of calcium ions (Ca2+) across the plasma membrane plays an important role in this response, but the identity of Ca2+ channels involved has remained elusive. Here, we report that the Arabidopsis thaliana Ca2+-permeable channel OSCA1.3 controls stomatal closure during immunity. OSCA1.3 is rapidly phosphorylated upon perception of pathogen-associated molecular patterns (PAMPs). Biochemical and quantitative phospho-proteomics analyses reveal that the immune receptor associated cytosolic kinase BIK1 interacts with and phosphorylates the N-terminal cytosolic loop of OSCA1.3 within minutes of treatment with the peptidic PAMP flg22 derived from bacterial flagellin.
HostingRepositoryPanoramaPublic
AnnounceDate2020-09-11
AnnouncementXMLSubmission_2020-09-11_06:47:43.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterFrank Menke
SpeciesList scientific name: Arabidopsis thaliana; NCBI TaxID: 3702;
ModificationListPhospho
InstrumentXevo TQ-S
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-08-11 11:42:11ID requested
12020-09-11 06:47:44announced
Publication List
Thor K, Jiang S, Michard E, George J, Scherzer S, Huang S, Dindas J, Derbyshire P, Leitão N, DeFalco TA, Köster P, Hunter K, Kimura S, Gronnier J, Stransfeld L, Kadota Y, Bücherl CA, Charpentier M, Wrzaczek M, MacLean D, Oldroyd GED, Menke FLH, Roelfsema MRG, Hedrich R, Feijó J, Zipfel C, The calcium-permeable channel OSCA1.3 regulates plant stomatal immunity. Nature, 585(7826):569-573(2020) [pubmed]
Keyword List
submitter keyword: phosphorylation, calcium channel, immunity, plant
Contact List
Frank Menke
contact affiliationThe Sainsbury Laboratory
contact emailfrank.menke@tsl.ac.uk
lab head
Frank Menke
contact affiliationThe Sainsbury Laboratory
contact emailfrank.menke@tsl.ac.uk
dataset submitter
Full Dataset Link List
Panorama Public dataset URI