PXD020799

PXD020799 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Large bidirectional remodeling of the Myc-induced cell surface proteome in B-cells and prostate cells creates new opportunities for immunotherapy
Description	To identify how MYC overexpression remodels the cell surface proteome in a cell autologous fashion and in different cell types, we investigated the impact of MYC overexpression on ~800 surface proteins in three isogenic model cell lines either of B-cell or prostate cell origin that were engineered to contain either high or low MYC.
HostingRepository	MassIVE
AnnounceDate	2021-01-28
AnnouncementXML	Submission_2021-01-28_14:27:19.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Kevin Leung
SpeciesList	scientific name: Homo sapiens; common name: human; NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl; Label:13C(6)15N(2); Label:13C(6)15N(4); Dimethyl; Dimethyl:2H(4)13C(2); deglycosylated asparagine
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-07 19:40:20	ID requested
⏵ 1	2021-01-28 14:27:20	announced

Publication List

Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA, Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy. Proc Natl Acad Sci U S A, 118(4):(2021) [pubmed]

Chen W, Mou KY, Solomon P, Aggarwal R, Leung KK, Wells JA, Large remodeling of the Myc-induced cell surface proteome in B cells and prostate cells creates new opportunities for immunotherapy. Proc Natl Acad Sci U S A, 118(4):(2021) [pubmed]

Keyword List

submitter keyword: Oncogene MYC, Surfaceome, Immunotherapy

submitter keyword: Oncogene MYC, Surfaceome, Immunotherapy

Contact List

James Wells
contact affiliation	UCSF
contact email	jim.wells@ucsf.edu
lab head
Kevin Leung
contact affiliation	UCSF
contact email	kevin.leung@ucsf.edu
dataset submitter

Full Dataset Link List

MassIVE dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000085930/

MassIVE dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://massive.ucsd.edu/MSV000085930/