PXD020770

PXD020770 is an original dataset announced via ProteomeXchange.

Title	Proteome and Phosphoproteome of AhR-dependent non-genomic signaling in endotoxin-activated macrophages
Description	Emerging studies revealed an immunomodulatory role of the Aryl hydrocarbon receptor (AhR), a receptor sensing environmental contaminants, and involved in their detoxification. Besides its function as a transcription factor, AhR can participate in non-genomic signaling through ubiquitination and phosphorylation-dependent processes. In this study, a multi-PTM-omics approach, including proteome, ubiquitome, and phosphoproteome, was utilized to examine mechanisms of non-genomic AhR-signaling in endotoxin-activated monocyte-derived macrophages. This dataset entails proteome and phosphoproteome data.
HostingRepository	PRIDE
AnnounceDate	2021-03-30
AnnouncementXML	Submission_2021-03-30_12:23:09.959.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Henning Großkopf
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	phosphorylated residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-06 02:08:15	ID requested
⏵ 1	2021-03-30 12:23:10	announced

Dataset with its publication pending

submitter keyword: AhR, Macrophages, Human, Phosphoproteome, Proteome, LC-MS/MS

Martin von Bergen
contact affiliation	Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ,Leipzig, Germany
contact email	martin.vonbergen@ufz.de
lab head
Henning Großkopf
contact affiliation	Molecular Systems Biology Helmholtz Centre for Environmental Research GmbH - UFZ Leipzig, Germany
contact email	henning.grosskopf@ufz.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/03/PXD020770

PRIDE project URI

• PRIDE
  1. PXD020770
     1. Label: PRIDE project
     2. Name: Proteome and Phosphoproteome of AhR-dependent non-genomic signaling in endotoxin-activated macrophages