PXD020732

PXD020732 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity
Description	Actin was acetylated on lysine residues with acetic anhydride to determine its impaction on the contractile properties of the thin filaments including, actin's ability to undergo crossbridge cycling with myosin, actin's affinity for tropomyosin, and the impact of actin acetylation on calcium regulated thin filament activation
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_08:51:36.721.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020732
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	D. Brian Foster
SpeciesList	scientific name: Oryctolagus cuniculus (Rabbit); NCBI TaxID: 9986;
ModificationList	acetylated residue
Instrument	Orbitrap Fusion Lumos

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-08-05 03:09:56	ID requested
1	2020-09-04 03:50:30	announced
2	2020-09-06 23:55:22	announced	2020-09-07: Updated publication reference for PubMed record(s): 32873710. 2020-09-07: Updated publication reference for DOI(s): 10.1074/jbc.RA120.015277.
⏵ 3	2023-11-14 08:51:44	announced	2023-11-14: Updated project metadata.

Publication List

Schmidt W, Madan A, Foster DB, Cammarato A, Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity. J Biol Chem, 295(46):15527-15539(2020) [pubmed]
10.6019/PXD020732;

Schmidt W, Madan A, Foster DB, Cammarato A, Lysine acetylation of F-actin decreases tropomyosin-based inhibition of actomyosin activity. J Biol Chem, 295(46):15527-15539(2020) [pubmed]

10.6019/PXD020732;

Keyword List

submitter keyword: lysine acetylation, myosin,actin, thin filament, tropomyosin, in vitro motility

submitter keyword: lysine acetylation, myosin,actin, thin filament, tropomyosin, in vitro motility

Contact List

Brian Foster
contact affiliation	Johns Hopkins School of Medicine, Division of Cardiology
contact email	dbrianfoster@jhmi.edu
lab head
D. Brian Foster
contact affiliation	Johns Hopkins University School of Medicine
contact email	dbrianfoster@jhmi.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD020732
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD020732

PRIDE project URI

Repository Record List

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