PXD020697
PXD020697 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | IFITM3 BioID Interactomes in B-ALL and MCL |
| Description | To determine the roles of membrane associated IFITM3 in BCR-signalling in B-cell malignancies we expressed N-terminal BirA-IFITM3-Y20E fusion or BirA-EV control in patient derived B-ALL cells (PDX2) and Jeko1 Mantle cell lymphoma (MCL) cells. Additionally to examine the role of PIP3 binding residues in the conserved intracellular loop region a K83A/K104A mutated form of IFITM3-Y20E-BirA fusion and compared with basic patch unmutated. |
| HostingRepository | PRIDE |
| AnnounceDate | 2020-12-18 |
| AnnouncementXML | Submission_2020-12-17_23:30:35.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Mark Robinson |
| SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
| ModificationList | biotinylated residue |
| Instrument | Orbitrap Fusion |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2020-08-03 02:40:04 | ID requested | |
| ⏵ 1 | 2020-12-17 23:30:36 | announced |
Publication List
| Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, Nix MA, Klemm L, Chen CW, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, Jung JU, Weinstock DM, Manalis SR, Diamond MS, Vaidehi N, M, ΓΌ, schen M, cells. Nature, 588(7838):491-497(2020) [pubmed] |
Keyword List
| submitter keyword: Human B-ALL MCL B-cells |
Contact List
| Markus Muschen | |
|---|---|
| contact affiliation | Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA, USA |
| contact email | mmuschen@coh.org |
| lab head | |
| Mark Robinson | |
| contact affiliation | City of Hope |
| contact email | marrobinson@coh.org |
| dataset submitter | |
Full Dataset Link List
| Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD020697 |
| PRIDE project URI |
Repository Record List
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