PXD020696
PXD020696 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | IFITM3 amino acid mutants phosphoproteomics |
Description | To investigate the role of IFITM3 in B-ALL, patient derived xenograft cells PDX2 were transduced with either a the constitutively membrane associated IFITM3-Y20E mutant or EV control. Additional mutation of PIP3 binding sites within the conserved internal loop region - K83/K104 or R85/R87/K88 - were introduced to test the predicted function of these sites. |
HostingRepository | PRIDE |
AnnounceDate | 2020-12-18 |
AnnouncementXML | Submission_2020-12-17_23:31:18.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Mark Robinson |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Fusion Lumos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-08-03 02:40:04 | ID requested | |
⏵ 1 | 2020-12-17 23:31:19 | announced |
Publication List
Lee J, Robinson ME, Ma N, Artadji D, Ahmed MA, Xiao G, Sadras T, Deb G, Winchester J, Cosgun KN, Geng H, Chan LN, Kume K, Miettinen TP, Zhang Y, Nix MA, Klemm L, Chen CW, Chen J, Khairnar V, Wiita AP, Thomas-Tikhonenko A, Farzan M, Jung JU, Weinstock DM, Manalis SR, Diamond MS, Vaidehi N, M, ΓΌ, schen M, cells. Nature, 588(7838):491-497(2020) [pubmed] |
Keyword List
submitter keyword: PDX B-ALL B-cell |
Contact List
Markus Muschen | |
---|---|
contact affiliation | Department of Systems Biology, City of Hope Comprehensive Cancer Center, CA, USA |
contact email | mmuschen@coh.org |
lab head | |
Mark Robinson | |
contact affiliation | City of Hope |
contact email | marrobinson@coh.org |
dataset submitter |
Full Dataset Link List
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD020696 |
PRIDE project URI |
Repository Record List
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