PXD020673

PXD020673 is an original dataset announced via ProteomeXchange.

Title	Effects of AKT inhibition in the pancreatic cancer cell proteome
Description	The AKT pathway is a major regulator of human pancreatic adenocarcinoma progression and a key pharmacological target. The mechanisms of adaptation to long-term silencing of AKT isoforms of human and mouse pancreatic adenocarcinoma cancer cells were studied.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_04:28:36.564.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Enrique Santamaría
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iTRAQ8plex-116 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-31 07:06:01	ID requested
⏵ 1	2021-09-09 04:28:37	announced

Arasanz H, Hern, á, ndez C, Bocanegra A, Chocarro L, Zuazo M, Gato M, Ausin K, Santamar, í, a E, Fern, á, ndez-Irigoyen J, Fernandez G, Santamaria E, Rodr, í, guez C, Blanco-Luquin I, Vera R, Escors D, Kochan G, Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition. Cancers (Basel), 12(8):(2020) [pubmed]

submitter keyword: proteomics, AKT, cancer, adenocarcinoma, pancreas

Enrique Santamaria
contact affiliation	Proteored-isciii Proteomics Platform-Navarrabiomed (Pamplona-Spain)
contact email	esantamma@navarra.es
lab head
Enrique Santamaría
contact affiliation	Proteomics unit
contact email	esantamma@navarra.es
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020673

PRIDE project URI

• PRIDE
  1. PXD020673
     1. Label: PRIDE project
     2. Name: Effects of AKT inhibition in the pancreatic cancer cell proteome