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PXD020636

PXD020636 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleA structural mechanism for PP2A-B56alpha inhibition by CIP2A
DescriptionChemical cross-linking coupled to mass spectrometry was used to study the structure of the oncoprotein CIP2A and its interaction with the B56alpha regulatory subunit of protein phosphatase 2A. Cross-linking was performed using disuccinimidyl suberate (DSS) or a combination of pimelic dihydrazide (PDH) and the coupling reagent DMTMM.
HostingRepositoryPRIDE
AnnounceDate2022-10-21
AnnouncementXMLSubmission_2022-10-21_01:39:40.948.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlexanderLeitner
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-29 06:25:14ID requested
12022-10-21 01:39:41announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Chemical cross-linking
DSS
PDH
DMTMM
structural proteomics
protein phosphatase 2A
Contact List
AlexanderLeitner
contact affiliationETH Zurich, Institute of Molecular Systems Biology, Zurich, Switzerland
contact emailleitner@imsb.biol.ethz.ch
lab head
AlexanderLeitner
contact affiliationETH Zurich, Institute of Molecular Systems Biology
contact emailleitner@imsb.biol.ethz.ch
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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