PXD020615

PXD020615 is an original dataset announced via ProteomeXchange.

Title	MASH Explorer: A Universal Software Environment for Top-Down Proteomics
Description	MASH Explorer, a universal, comprehensive, and user-friendly software environment for top-down proteomics. MASH Explorer integrates multiple spectral deconvolution and database searching algorithms into a single, universal platform which can process top-down proteomics data from various vendor formats, for the first time. It addresses the urgent need in the rapidly growing top-down proteomics community and is freely available to all users worldwide. With the critical need and tremendous support from the community, we envision this MASH Explorer software package will play an integral role in advancing top-down proteomics to realize its full potential for biomedical research.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_01:16:44.257.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zhijie Wu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	2-pyrrolidone-5-carboxylic acid (Gln)
Instrument	maXis

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-28 17:20:21	ID requested
⏵ 1	2021-09-09 01:16:45	announced

Wu Z, Roberts DS, Melby JA, Wenger K, Wetzel M, Gu Y, Ramanathan SG, Bayne EF, Liu X, Sun R, Ong IM, McIlwain SJ, Ge Y, MASH Explorer: A Universal Software Environment for Top-Down Proteomics. J Proteome Res, 19(9):3867-3876(2020) [pubmed]

Chen B, Lin Z, Zhu Y, Jin Y, Larson E, Xu Q, Fu C, Zhang Z, Zhang Q, Pritts WA, Ge Y, Middle-Down Multi-Attribute Analysis of Antibody-Drug Conjugates with Electron Transfer Dissociation. Anal Chem, 91(18):11661-11669(2019) [pubmed]

submitter keyword: Top-down proteomics

Data analysis software

Proteoform characterization

Intact Protein Analysis

Dr. Ying Ge
contact affiliation	Professor, Department of Cell and Regenerative Biology Professor, Department of Chemistry Director of Mass Spectrometry Human Proteomics Program School of Medicine and Public Health University of Wisconsin-Madison
contact email	ying.ge@wisc.edu
lab head
Zhijie Wu
contact affiliation	University of Wisconsin - Madison
contact email	zwu227@wisc.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020615

PRIDE project URI

• PRIDE
  1. PXD020615
     1. Label: PRIDE project
     2. Name: MASH Explorer: A Universal Software Environment for Top-Down Proteomics