PXD020614 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes |
Description | Transmissible cancers are spread via the passage of malignant cells. The survival of the Tasmanian devil, the largest marsupial carnivore, is threatened by two independent transmissible cancers, devil facial tumour (DFT) 1 and devil facial tumour 2 (DFT2). To aid the development of a peptide vaccine and to interrogate how histocompatibility barriers can be overcome, we analysed the peptides bound to Major Histocompatibility Complex class I molecules from the Tasmanian devil and its transmissible tumours. |
HostingRepository | PRIDE |
AnnounceDate | 2023-11-14 |
AnnouncementXML | Submission_2023-11-14_08:51:36.310.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Sri Ramarathinam |
SpeciesList | scientific name: Sarcophilus harrisii; NCBI TaxID: 9305; |
ModificationList | monohydroxylated residue; acetylated residue; deamidated residue |
Instrument | Q Exactive |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-07-28 05:10:21 | ID requested | |
1 | 2021-02-07 23:28:24 | announced | |
⏵ 2 | 2023-11-14 08:51:42 | announced | 2023-11-14: Updated project metadata. |
Publication List
Gastaldello A, Ramarathinam SH, Bailey A, Owen R, Turner S, Kontouli N, Elliott T, Skipp P, Purcell AW, Siddle HV, The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif. Immunology, 163(2):169-184(2021) [pubmed] |
Keyword List
submitter keyword: contagious cancer, MHC, marsupial,Transmissible cancer, Tasmanian devil, immunopeptidome |
Contact List
Anthony Wayne Purcell |
contact affiliation | Deputy Head (Research), Department of Biochemistry and Molecular Biology, Head Immunoproteomics Laboratory, Infection and Immunity Program, Monash Biomedicine Discovery Institute, Monash University, Victoria, Australia |
contact email | anthony.purcell@monash.edu |
lab head | |
Sri Ramarathinam |
contact affiliation | Monash University |
contact email | sri.ramarathinam@monash.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD020614 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020614
- Label: PRIDE project
- Name: Passage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes