PXD020587
PXD020587 is an original dataset announced via ProteomeXchange.
Dataset Summary
Title | The membrane protein profiles from different lung cancer cell lines. The different mutation harboring in different cell line might reflect different phenotype even though they have same cancer type. |
Description | The membrane proteins are the main receptors that received the signals out of the cells. The abnormal of these membrane proteins will cause the wrong signal transduction which leads to loss of functions or diseases. To fix the abnormal signaling pathways, the intervention of the treatment mostly will target in these membrane receptors to inhibit the abnormal transduction cascade like the tyrosin kinase inhibitors in lung cancer. However, the lung cancer cell line have different kinds of mutation, and each of them have its own unique phenotype and drug response. The study of the membrane protein profiles from these cell lines with different mutation might help to correlate the mutation site and phenotype of the cell lines. |
HostingRepository | jPOST |
AnnounceDate | 2020-07-27 |
AnnouncementXML | Submission_2022-09-18_03:43:23.467.xml |
DigitalObjectIdentifier | |
ReviewLevel | Non peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | YU- Teng Jheng |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | unknown modification; alpha-amino acetylated residue; L-methionine sulfoxide; unknown modification |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
---|---|---|---|
0 | 2020-07-27 02:14:47 | ID requested | |
1 | 2020-07-27 02:14:51 | announced | |
2 | 2021-02-04 17:31:31 | announced | 2021-02-04: Updated FTP location. |
⏵ 3 | 2022-09-18 03:43:23 | announced | 2022-09-18: Updated FTP location. |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Lung cancer, Proteomics, Membrane proteins |
Contact List
Chia-Li Han | |
---|---|
lab head | |
YU- Teng Jheng | |
contact affiliation | Genome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei 10617, Taiwan |
dataset submitter |
Full Dataset Link List
jPOST dataset URI |
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000923/ |