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PXD020587

PXD020587 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe membrane protein profiles from different lung cancer cell lines. The different mutation harboring in different cell line might reflect different phenotype even though they have same cancer type.
DescriptionThe membrane proteins are the main receptors that received the signals out of the cells. The abnormal of these membrane proteins will cause the wrong signal transduction which leads to loss of functions or diseases. To fix the abnormal signaling pathways, the intervention of the treatment mostly will target in these membrane receptors to inhibit the abnormal transduction cascade like the tyrosin kinase inhibitors in lung cancer. However, the lung cancer cell line have different kinds of mutation, and each of them have its own unique phenotype and drug response. The study of the membrane protein profiles from these cell lines with different mutation might help to correlate the mutation site and phenotype of the cell lines.
HostingRepositoryjPOST
AnnounceDate2020-07-27
AnnouncementXMLSubmission_2022-09-18_03:43:23.467.xml
DigitalObjectIdentifier
ReviewLevelNon peer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYU- Teng Jheng
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListunknown modification; alpha-amino acetylated residue; L-methionine sulfoxide; unknown modification
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-27 02:14:47ID requested
12020-07-27 02:14:51announced
22021-02-04 17:31:31announced2021-02-04: Updated FTP location.
32022-09-18 03:43:23announced2022-09-18: Updated FTP location.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Lung cancer, Proteomics, Membrane proteins
Contact List
Chia-Li Han
lab head
YU- Teng Jheng
contact affiliationGenome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei 10617, Taiwan
dataset submitter
Full Dataset Link List
jPOST dataset URI
Dataset FTP location
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