PXD020556

PXD020556 is an original dataset announced via ProteomeXchange.

Title	Autophagy-mediated metabolic effects of aspirin
Description	Aspirin caused a transient reduction of general protein acetylation in blood leukocytes, accompanied by the induction of autophagy. These effects on global protein acetylation could not be attributed to the mere inhibition of EP300, but most likely through the inhibition of other acetyltransferases. To investigate this possibility, we performed a quantitative label-free enriched acetylome analysis, search-ing for proteins that are deacetylated upon EP300 knockout and/or salicylate treatment.
HostingRepository	PRIDE
AnnounceDate	2021-01-08
AnnouncementXML	Submission_2021-01-08_05:55:01.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Valentin SABATET
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF-X

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-24 02:45:13	ID requested
⏵ 1	2021-01-08 05:55:02	announced

Castoldi F, Humeau J, Martins I, Lachkar S, Loew D, Dingli F, Durand S, Enot D, Bossut N, Chery A, Aprahamian F, Demont Y, Opolon P, Signolle N, Sauvat A, Semeraro M, Bezu L, Baracco EE, Vacchelli E, Pol JG, L, é, vesque S, Bloy N, Sica V, Maiuri MC, Kroemer G, Pietrocola F, Autophagy-mediated metabolic effects of aspirin. Cell Death Discov, 6(1):129(2020) [pubmed]

submitter keyword: Cells HCT WT and EP300 KO, aspirin

Damarys Loew
contact affiliation	Head of the Curie Institute Mass Spectrometry Platform
contact email	damarys.loew@curie.fr
lab head
Valentin SABATET
contact affiliation	Curie Institute
contact email	valentin.sabatet@curie.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/01/PXD020556

PRIDE project URI

• PRIDE
  1. PXD020556
     1. Label: PRIDE project
     2. Name: Autophagy-mediated metabolic effects of aspirin