PXD020508

PXD020508 is an original dataset announced via ProteomeXchange.

Title	Proteome of bovine granulosa cells and extracellular vesicles from follicular fluid
Description	The follicular fluid (FF) fills the interior of ovarian antral follicle and provides the microenvironment for oocyte growth and acquisition of its competence to ovulate and latter support early embryo development. The FF is derived from both blood plasma and secretion of different types of follicular cells. It contains also extracellular vesicles (EVs), including exosomes, small membrane-coated EVs with 30-150 nm in diameter, which participate in cell-to cell communication and signaling by transferring their cargo of different types of RNAs, proteins and lipids into the oocyte or follicular cells. To date most studies have focused on studying the ffEVs miRNAs cargo and showing that miRNAs can influence oocyte competence and further embryo development. However, ffEVs protein cargo, which could have a direct contribution after being uptake by the oocyte or follicular cells have been less studies.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:24:38.414.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020508
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Valerie LABAS
SpeciesList	scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationList	No PTMs are included in the dataset
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-22 08:17:54	ID requested
1	2021-08-17 06:14:22	announced
⏵ 2	2024-10-22 05:24:40	announced	2024-10-22: Updated project metadata.

Uzbekova S, Almi, ñ, ana C, Labas V, Teixeira-Gomes AP, Combes-Soia L, Tsikis G, Carvalho AV, Uzbekov R, Singina G, Protein Cargo of Extracellular Vesicles From Bovine Follicular Fluid and Analysis of Their Origin From Different Ovarian Cells. Front Vet Sci, 7():584948(2020) [pubmed]

10.3389/fvets.2020.584948;

10.6019/PXD020508;

submitter keyword: exosomes,bovine, granulosa cells

Svetlana UZBEKOVA
contact affiliation	Centre INRAE Val de Loire UMR physiologie de la Reproduction et des comportements
contact email	svetlana.uzbekova@inrae.fr
lab head
Valerie LABAS
contact affiliation	INRAE
contact email	valerie.labas@inrae.fr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD020508

PRIDE project URI

• PRIDE
  1. PXD020508
     1. Label: PRIDE project
     2. Name: Proteome of bovine granulosa cells and extracellular vesicles from follicular fluid