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PXD020508

PXD020508 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteome of bovine granulosa cells and extracellular vesicles from follicular fluid
DescriptionThe follicular fluid (FF) fills the interior of ovarian antral follicle and provides the microenvironment for oocyte growth and acquisition of its competence to ovulate and latter support early embryo development. The FF is derived from both blood plasma and secretion of different types of follicular cells. It contains also extracellular vesicles (EVs), including exosomes, small membrane-coated EVs with 30-150 nm in diameter, which participate in cell-to cell communication and signaling by transferring their cargo of different types of RNAs, proteins and lipids into the oocyte or follicular cells. To date most studies have focused on studying the ffEVs miRNAs cargo and showing that miRNAs can influence oocyte competence and further embryo development. However, ffEVs protein cargo, which could have a direct contribution after being uptake by the oocyte or follicular cells have been less studies.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:24:38.414.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD020508
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterValerie LABAS
SpeciesList scientific name: Bos taurus (Bovine); NCBI TaxID: 9913;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-22 08:17:54ID requested
12021-08-17 06:14:22announced
22024-10-22 05:24:40announced2024-10-22: Updated project metadata.
Publication List
Uzbekova S, Almi, ñ, ana C, Labas V, Teixeira-Gomes AP, Combes-Soia L, Tsikis G, Carvalho AV, Uzbekov R, Singina G, Protein Cargo of Extracellular Vesicles From Bovine Follicular Fluid and Analysis of Their Origin From Different Ovarian Cells. Front Vet Sci, 7():584948(2020) [pubmed]
10.3389/fvets.2020.584948;
10.6019/PXD020508;
Keyword List
submitter keyword: exosomes,bovine, granulosa cells
Contact List
Svetlana UZBEKOVA
contact affiliationCentre INRAE Val de Loire UMR physiologie de la Reproduction et des comportements
contact emailsvetlana.uzbekova@inrae.fr
lab head
Valerie LABAS
contact affiliationINRAE
contact emailvalerie.labas@inrae.fr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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