PXD020508 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteome of bovine granulosa cells and extracellular vesicles from follicular fluid |
Description | The follicular fluid (FF) fills the interior of ovarian antral follicle and provides the microenvironment for oocyte growth and acquisition of its competence to ovulate and latter support early embryo development. The FF is derived from both blood plasma and secretion of different types of follicular cells. It contains also extracellular vesicles (EVs), including exosomes, small membrane-coated EVs with 30-150 nm in diameter, which participate in cell-to cell communication and signaling by transferring their cargo of different types of RNAs, proteins and lipids into the oocyte or follicular cells. To date most studies have focused on studying the ffEVs miRNAs cargo and showing that miRNAs can influence oocyte competence and further embryo development. However, ffEVs protein cargo, which could have a direct contribution after being uptake by the oocyte or follicular cells have been less studies. |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:24:38.414.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD020508 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Valerie LABAS |
SpeciesList | scientific name: Bos taurus (Bovine); NCBI TaxID: 9913; |
ModificationList | No PTMs are included in the dataset |
Instrument | LTQ Orbitrap Velos |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-07-22 08:17:54 | ID requested | |
1 | 2021-08-17 06:14:22 | announced | |
⏵ 2 | 2024-10-22 05:24:40 | announced | 2024-10-22: Updated project metadata. |
Publication List
Uzbekova S, Almi, ñ, ana C, Labas V, Teixeira-Gomes AP, Combes-Soia L, Tsikis G, Carvalho AV, Uzbekov R, Singina G, Protein Cargo of Extracellular Vesicles From Bovine Follicular Fluid and Analysis of Their Origin From Different Ovarian Cells. Front Vet Sci, 7():584948(2020) [pubmed] |
10.3389/fvets.2020.584948; |
10.6019/PXD020508; |
Keyword List
submitter keyword: exosomes,bovine, granulosa cells |
Contact List
Svetlana UZBEKOVA |
contact affiliation | Centre INRAE Val de Loire UMR physiologie de la Reproduction et des comportements |
contact email | svetlana.uzbekova@inrae.fr |
lab head | |
Valerie LABAS |
contact affiliation | INRAE |
contact email | valerie.labas@inrae.fr |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/08/PXD020508 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020508
- Label: PRIDE project
- Name: Proteome of bovine granulosa cells and extracellular vesicles from follicular fluid