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PXD020467

PXD020467 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic approach for searching of universal, tissue-specific and line-specific markers of extracellular vesicles in lung and colorectal adenocarcinoma cell lines:extracellular vesicles only
DescriptionThe efficiency of anticancer therapy depends heavily on the molecular features of the tumor. Since tumor-derived extracellular vesicles, including exosomes, contain proteins that are characteristic for producer cells and could be detected in biological fluids, they are of great interest for screening of predictive biomarkers. We have performed label-free mass spectrometric profiling of extracellular vesicles originated from human colon cancer cell lines Caco-2, HT-26 and HCT-116, and from lung cancer cell lines NCI-H23 and A549.
HostingRepositoryPRIDE
AnnounceDate2021-09-09
AnnouncementXMLSubmission_2021-09-09_03:04:23.647.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterSvetlana Novikova
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-21 03:12:09ID requested
12021-09-09 03:04:25announced
Publication List
Novikova S, Shushkova N, Farafonova T, Tikhonova O, Kamyshinsky R, Zgoda V, Proteomic Approach for Searching for Universal, Tissue-Specific, and Line-Specific Markers of Extracellular Vesicles in Lung and Colorectal Adenocarcinoma Cell Lines. Int J Mol Sci, 21(18):(2020) [pubmed]
Keyword List
submitter keyword: extracellular vesicles
exosomes
proteomics
mass-spectrometry
colon cancer
lung cancer
biomarkers
Contact List
Victor Zgoda
contact affiliationLaboratory of Systems Biology, Institute of Biomedical Chemistry, Moscow
contact emailvictor.zgoda@gmail.com
lab head
Svetlana Novikova
contact affiliationInstitute of Biomedical Bhemistry (IBMC), Moscow
contact emailnovikova.s.e3101@gmail.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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