PXD020316

PXD020316 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Neuronal cells from ASL patients
Description	This study describes altered CREB-dependent activity related transcription, and disrupted synaptic composition as common pathological features in ALS. These aberrations are restored by Apamin and XE991, two K+ channel blockers targeting the SK and Kv7 channels and modulating neuronal excitability.This study describes altered CREB-dependent activity related transcription, and disrupted synaptic composition as common pathological features in ALS. These aberrations are restored by Apamin and XE991, two K+ channel blockers targeting the SK and Kv7 channels and modulating neuronal excitability.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:21:48.282.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Chiara guerrera
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-13 00:07:27	ID requested
1	2021-05-11 04:24:14	announced
⏵ 2	2024-10-22 05:21:48	announced	2024-10-22: Updated project metadata.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: ASL,motoneurons, label free

submitter keyword: ASL,motoneurons, label free

Contact List

GUERRERA Isa Chuara
contact affiliation	Proteomic Platform Necker, INSERM US24, SFR Necker Université de Paris
contact email	chiara.guerrera@inserm.fr
lab head
Chiara guerrera
contact affiliation	Necker proteomics, INSERM
contact email	chiara.guerrera@inserm.fr
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD020316
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/05/PXD020316

PRIDE project URI

Repository Record List

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