PXD020277

PXD020277 is an original dataset announced via ProteomeXchange.

Title	Site-specific N-glycoproteomic analysis of Intrahepatic cholangiocarcinoma and Hepatocellular carcinoma
Description	In this study,we performed integrated glycoproteomic and global proteomic analysis of tumor tissues of ICC and HCC to investigate the differences in site-specific glycosylation and proteins between ICC and HCC tumors. The paired paracancer tissue were also included as controls to determine the site-specific glycosylation changes in ICC and HCC tumors. The alteration extents in glycopeptide, global proteome, and normalized glycosylation in different sample groups were systematically compared.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:38:52.780.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Jun Li
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-09 03:59:54	ID requested
1	2022-08-11 09:29:06	announced
⏵ 2	2024-10-22 05:38:57	announced	2024-10-22: Updated project metadata.

10.1002/1878-0261.13147;

Li J, Zhao T, Li J, Shen J, Jia L, Zhu B, Dang L, Ma C, Liu D, Mu F, Hu L, Sun S, Precision N-glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma. Mol Oncol, 16(11):2135-2152(2022) [pubmed]

submitter keyword: Intrahepatic cholangiocarcinoma(ICC), intact glycopeptide, site-specific glycosylation, Hepatocellular carcinoma(HCC), glycoproteome, LC-MS/MS

Shisheng Sun
contact affiliation	Northwest University
contact email	suns@nwu.edu.cn
lab head
Jun Li
contact affiliation	Northwest University
contact email	jun.li@nwu.edu.cn
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/08/PXD020277

PRIDE project URI

• PRIDE
  1. PXD020277
     1. Label: PRIDE project
     2. Name: Site-specific N-glycoproteomic analysis of Intrahepatic cholangiocarcinoma and Hepatocellular carcinoma