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PXD020277

PXD020277 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleSite-specific N-glycoproteomic analysis of Intrahepatic cholangiocarcinoma and Hepatocellular carcinoma
DescriptionIn this study,we performed integrated glycoproteomic and global proteomic analysis of tumor tissues of ICC and HCC to investigate the differences in site-specific glycosylation and proteins between ICC and HCC tumors. The paired paracancer tissue were also included as controls to determine the site-specific glycosylation changes in ICC and HCC tumors. The alteration extents in glycopeptide, global proteome, and normalized glycosylation in different sample groups were systematically compared.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:38:52.780.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterJun Li
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentOrbitrap Fusion Lumos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-09 03:59:54ID requested
12022-08-11 09:29:06announced
22024-10-22 05:38:57announced2024-10-22: Updated project metadata.
Publication List
10.1002/1878-0261.13147;
Li J, Zhao T, Li J, Shen J, Jia L, Zhu B, Dang L, Ma C, Liu D, Mu F, Hu L, Sun S, Precision N-glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma. Mol Oncol, 16(11):2135-2152(2022) [pubmed]
Keyword List
submitter keyword: Intrahepatic cholangiocarcinoma(ICC), intact glycopeptide, site-specific glycosylation, Hepatocellular carcinoma(HCC), glycoproteome, LC-MS/MS
Contact List
Shisheng Sun
contact affiliationNorthwest University
contact emailsuns@nwu.edu.cn
lab head
Jun Li
contact affiliationNorthwest University
contact emailjun.li@nwu.edu.cn
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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