PXD020265

PXD020265 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Exposure to particulate matter (PM) pollution has direct impacts on the respiratory organs. However, the molecular alterations underlying PM-induced pulmonary injury remain unclear. In this study, we aimed to investigate the effects and pathomechanism of PM in lungs.
Description	The rat model was previously reported as whole-body exposure to traffic-related PM1 pollutant (PM1 group), high-efficiency particulate air-filtered gaseous pollutant (GAS group), and clean air control (CTL group) for 3 and 6 months. We performed lung function and histological examinations as well as quantitative proteomics analysis to unravel the structural and molecular changes in rat lungs upon sub-chronic and chronic exposures of PM1. Our study illustrated earlier lung injury prior to lung function decline and the underlying pathomechanism associated with traffic-related PM1-induced lung injury.
HostingRepository	jPOST
AnnounceDate	2020-07-27
AnnouncementXML	Submission_2022-09-18_03:03:17.319.xml
DigitalObjectIdentifier
ReviewLevel	Non peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	YU- Teng Jheng
SpeciesList	scientific name: Rattus rattus (Black rat); NCBI TaxID: 10117;
ModificationList	L-methionine sulfoxide; alpha-amino acetylated residue; unknown modification; unknown modification; TMT6plex reporter+balance reagent acylated N-terminal; TMT6plex reporter+balance reagent N-acylated residue
Instrument	instrument

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-08 21:54:36	ID requested
1	2020-07-27 02:17:17	announced
2	2021-02-04 16:56:56	announced	2021-02-04: Updated FTP location.
⏵ 3	2022-09-18 03:03:17	announced	2022-09-18: Updated FTP location.

Publication List

Dataset with its publication pending

Dataset with its publication pending

Keyword List

submitter keyword: Traffic-related air pollution, particulate matter, lung injury, proteomics

submitter keyword: Traffic-related air pollution, particulate matter, lung injury, proteomics

Contact List

Chia-Li Han
lab head
YU- Teng Jheng
contact affiliation	Genome and Systems Biology Degree Program, Academia Sinica and National Taiwan University, Taipei 10617, Taiwan
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000909/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000909/