PXD020238

PXD020238 is an original dataset announced via ProteomeXchange.

Title	A human BCRP (ABCG2) cell line without MDR1 (ABCB1) background –improved models for drug efflux studies using CRISPR-Cas
Description	Proteomics data of two MDCK-cMDR1 KO cell lines expressing either hBCRP or hMDR1 drug transporters, generated with CRISPR-Cas9.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:14:48.099.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Christine Wegler
SpeciesList	scientific name: Canis familiaris (Dog) (Canis lupus familiaris); NCBI TaxID: 9615;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-07 08:04:33	ID requested
1	2020-11-09 04:51:35	announced
⏵ 2	2024-10-22 05:14:48	announced	2024-10-22: Updated project metadata.

Dataset with its publication pending

submitter keyword: MDR1, CRISPR-Cas9, MDCK, BCRP,Drug transporters, cell line

Per Artursson
contact affiliation	Department of Pharmacy Uppsala University Box 580 SE-751 23 Uppsala, Sweden
contact email	per.artursson@farmaci.uu.se
lab head
Christine Wegler
contact affiliation	Uppsala University
contact email	christine.wegler@farmaci.uu.se
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/11/PXD020238

PRIDE project URI

• PRIDE
  1. PXD020238
     1. Label: PRIDE project
     2. Name: A human BCRP (ABCG2) cell line without MDR1 (ABCB1) background –improved models for drug efflux studies using CRISPR-Cas