PXD020192

PXD020192 is an original dataset announced via ProteomeXchange.

Title	Proteomic Profiling of the Human Tissue and Biological Fluid Proteome
Description	Here, we performed label-free liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) to profile the normal human proteome. In total, we analyzed 117 samples from 46 histologically normal tissues and organs at autopsy. Our high-resolution MS approach allowed for the quantification of 10,438 unique proteins. In order to expand our coverage of the human proteome, we combined our previously published biological fluid proteomic data from healthy individuals. We considered data from seven biological fluids, including urine, cerebrospinal fluid, synovial fluid, seminal plasma, sweat, cervical vaginal fluid, and nipple aspirate fluid. Overall, we generated tandem mass spectra corresponding to 13,028 unique human protein-coding genes.
HostingRepository	PRIDE
AnnounceDate	2020-10-29
AnnouncementXML	Submission_2020-10-29_06:55:11.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ashley Di Meo
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-03 17:21:31	ID requested
⏵ 1	2020-10-29 06:55:12	announced

Di Meo A, Sohaei D, Batruch I, Alexandrou P, Prassas I, Diamandis EP, Proteomic Profiling of the Human Tissue and Biological Fluid Proteome. J Proteome Res, 20(1):444-452(2021) [pubmed]

submitter keyword: mass spectrometry, LC-MS/MS, tissue proteome, biological fluid proteome, brain regions

Eleftherios P Diamandis
contact affiliation	Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada; Department of Clinical Biochemistry, University Health Network, Toronto, Canada
contact email	eleftherios.diamandis@sinaihealth.ca
lab head
Ashley Di Meo
contact affiliation	University of Toronto
contact email	ashley.dimeo@mail.utoronto.ca
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/10/PXD020192

PRIDE project URI

• PRIDE
  1. PXD020192
     1. Label: PRIDE project
     2. Name: Proteomic Profiling of the Human Tissue and Biological Fluid Proteome