PXD020186

PXD020186 is an original dataset announced via ProteomeXchange.

Title	The HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues
Description	A use case of the benign HLA-Ligand-Atlas is the prioritization of tumor-associated targets for e.g. peptide vaccination. Based on three glioblastoma samples, we illustrated how many of these peptides are covered in the benign dataset. The experimental and computational workflow for the isolation and identification of the glioblastoma immunopeptidomes is the same, as for all samples included in the HLA Ligand Atlas. As the three glioblastoma samples are not included in the HLA Ligand Atlas dataset, they have been deposited under a separate submission.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:21:11.205.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD020186
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ana Marcu
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Fusion Lumos

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-03 07:21:42	ID requested
1	2021-04-16 03:04:18	announced
2	2021-04-18 22:03:05	announced	2021-04-19: Updated publication reference for PubMed record(s): 33858848.
⏵ 3	2024-10-22 05:21:15	announced	2024-10-22: Updated project metadata.

10.1136/jitc-2020-002071;

Marcu A, Bichmann L, Kuchenbecker L, Kowalewski DJ, Freudenmann LK, Backert L, M, ü, hlenbruch L, Szolek A, L, ü, bke M, Wagner P, Engler T, Matovina S, Wang J, Hauri-Hohl M, Martin R, Kapolou K, Walz JS, Velz J, Moch H, Regli L, Silginer M, Weller M, L, ö, ffler MW, Erhard F, Schlosser A, Kohlbacher O, Stevanovi, ć S, Rammensee HG, Neidert MC, HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy. J Immunother Cancer, 9(4):(2021) [pubmed]

10.6019/PXD020186;

submitter keyword: Human, HLA, Glioblastoma, Immunopeptidomics

Hans-Georg Rammensee
contact affiliation	Department of Immunology, Interfaculty Institute for Cell Biology, Eberhard Karls University Tübingen
contact email	hgrhgr2017@gmx.de
lab head
Ana Marcu
contact affiliation	University of Tübingen, Interfaculty Institute for Cell Biology, Department of Immunology
contact email	anamarcu.pe@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD020186

PRIDE project URI

• PRIDE
  1. PXD020186
     1. Label: PRIDE project
     2. Name: The HLA-Ligand-Atlas. A resource of natural HLA ligands presented on benign tissues