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PXD020149

PXD020149 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleQuantitative proteomics combine with affinity MS revealed the molecular mechanism of ginsenoside anti-tumor effects
DescriptionThe Tandem Mass Tag (TMT) labeling quantitative proteomics technique acquired 55620 MS/MS spectra that identified 5499 proteins and 3045 modified proteins. Of these identified proteins, 224 differentially expressed proteins and modified proteins were significantly altered in non-small cell lung cancer cell lines. Bioinformatics tools for comprehensive analysis revealed that the Ras protein played a general regulatory role in many functional pathways and was probably the direct target protein of a compound in ginsenosides.
HostingRepositoryiProX
AnnounceDate2019-02-17
AnnouncementXMLSubmission_2020-07-02_01:45:45.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterWang Zhihua
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentTMT quantitation analysis
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-07-02 01:44:13ID requested
12020-07-02 01:45:46announced
Publication List
Wang Z, Kim U, Jiao Y, Li C, Guo Y, Ma X, Jiang M, Jiang Z, Hou Y, Bai G, Quantitative Proteomics Combined with Affinity MS Revealed the Molecular Mechanism of Ginsenoside Antitumor Effects. J Proteome Res, 18(5):2100-2108(2019) [pubmed]
Keyword List
submitter keyword: quantitative proteomics
Contact List
Wang Zhihua
contact affiliationNankai univerisity
contact email15822278821@163.com
lab head
Wang Zhihua
contact affiliationNankai univerisity
contact email15822278821@163.com
dataset submitter
Full Dataset Link List
iProX dataset URI