PXD020137

PXD020137 is an original dataset announced via ProteomeXchange.

Title	Naturally processed flucloxacillin haptenated HLA ligands
Description	This study has demonstrated that natural flucloxacillin haptenated HLA-B*57:01 ligands arepresented by antigen presenting cells through multiple pathways. Identification of such epitopes will help to define the chemical signals responsible for drug-induced immunological disease.
HostingRepository	PRIDE
AnnounceDate	2020-08-05
AnnouncementXML	Submission_2020-08-04_23:16:55.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	James Waddington
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	TripleTOF 5600

Revision	Datetime	Status	ChangeLog Entry
0	2020-07-01 06:13:59	ID requested
⏵ 1	2020-08-04 23:16:56	announced

Waddington JC, Meng X, Illing PT, Tailor A, Adair K, Whitaker P, Hamlett J, Jenkins RE, Farrell J, Berry N, Purcell AW, Naisbitt DJ, Park BK, Identification of Flucloxacillin-Haptenated HLA-B*57:01 Ligands: Evidence of Antigen Processing and Presentation. Toxicol Sci, 177(2):454-465(2020) [pubmed]

submitter keyword: Drug hypersensitivity, Flucloxacillin, HLA-B*57:01, DILI

Xiaoli Meng
contact affiliation	The University of Liverpool
contact email	xlmeng@liv.ac.uk
lab head
James Waddington
contact affiliation	The University of Liverpool
contact email	hljwaddi@liv.ac.uk
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/08/PXD020137

PRIDE project URI

• PRIDE
  1. PXD020137
     1. Label: PRIDE project
     2. Name: Naturally processed flucloxacillin haptenated HLA ligands