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PXD020100

PXD020100 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleEquine gluteal muscle LC-MSMS: Thoroughbred
DescriptionRecurrent exertional rhabdomyolysis (RER) develops in 5-10% of Thoroughbred racehorses. High-stress environments, nervous temperament, and diet influence the presentation of RER. RER-susceptibility is associated with alterations in intramuscular Ca2+ regulation with detrimental effects on mitochondria. Our study aims to determine underlying molecular drivers influencing RER-susceptibility by comparing the muscle proteome of control, RER-susceptible, and RER horses treated with dantrolene. Animals used in this study were Thoroughbred mares in race training between episodes of RER.
HostingRepositoryPRIDE
AnnounceDate2021-03-04
AnnouncementXMLSubmission_2021-03-04_14:18:00.320.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD020100
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterStephanie Valberg
SpeciesList scientific name: Equus caballus (Horse); NCBI TaxID: 9796;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-29 06:03:03ID requested
12021-03-04 14:18:00announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Equine, Muscle, Thoroughbred, RER
Contact List
Stephanie Valberg
contact affiliationMichigan State University
contact emailvalbergs@msu.edu
lab head
Stephanie Valberg
contact affiliationMichigan State University
contact emailvalbergs@msu.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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