PXD020100 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Equine gluteal muscle LC-MSMS: Thoroughbred |
Description | Recurrent exertional rhabdomyolysis (RER) develops in 5-10% of Thoroughbred racehorses. High-stress environments, nervous temperament, and diet influence the presentation of RER. RER-susceptibility is associated with alterations in intramuscular Ca2+ regulation with detrimental effects on mitochondria. Our study aims to determine underlying molecular drivers influencing RER-susceptibility by comparing the muscle proteome of control, RER-susceptible, and RER horses treated with dantrolene. Animals used in this study were Thoroughbred mares in race training between episodes of RER. |
HostingRepository | PRIDE |
AnnounceDate | 2021-03-04 |
AnnouncementXML | Submission_2021-03-04_14:18:00.320.xml |
DigitalObjectIdentifier | https://dx.doi.org/10.6019/PXD020100 |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Supported dataset by repository |
PrimarySubmitter | Stephanie Valberg |
SpeciesList | scientific name: Equus caballus (Horse); NCBI TaxID: 9796; |
ModificationList | TMT6plex-126 reporter+balance reagent acylated residue; acetylated residue; monohydroxylated residue; iodoacetamide derivatized residue |
Instrument | Q Exactive HF |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-29 06:03:03 | ID requested | |
⏵ 1 | 2021-03-04 14:18:00 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: Equine, Muscle, Thoroughbred, RER |
Contact List
Stephanie Valberg |
contact affiliation | Michigan State University |
contact email | valbergs@msu.edu |
lab head | |
Stephanie Valberg |
contact affiliation | Michigan State University |
contact email | valbergs@msu.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020100
- Label: PRIDE project
- Name: Equine gluteal muscle LC-MSMS: Thoroughbred