PXD020089

PXD020089 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	IRG1 Inflammasome Proteomics Experiments
Description	BMDMs of indicated phenotypes were stimulated with LPS for 24h and analyzed or restimulated with LPS for additional 3h and analyzed. In some experiments 1mM itaconate was added at 4h of LPS first stimulation.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-09_00:54:10.853.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Kate Lizotte
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-29 02:19:09	ID requested
⏵ 1	2021-09-09 00:54:11	announced

Publication List

Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN, Itaconate confers tolerance to late NLRP3 inflammasome activation. Cell Rep, 34(10):108756(2021) [pubmed]

Bambouskova M, Potuckova L, Paulenda T, Kerndl M, Mogilenko DA, Lizotte K, Swain A, Hayes S, Sheldon RD, Kim H, Kapadnis U, Ellis AE, Isaguirre C, Burdess S, Laha A, Amarasinghe GK, Chubukov V, Roddy TP, Diamond MS, Jones RG, Simons DM, Artyomov MN, Itaconate confers tolerance to late NLRP3 inflammasome activation. Cell Rep, 34(10):108756(2021) [pubmed]

Keyword List

submitter keyword: IRG1, BMDM, LPS, LCMS, itaconylation, Proteomics

submitter keyword: IRG1, BMDM, LPS, LCMS, itaconylation, Proteomics

Contact List

Sebastian Hayes
contact affiliation	Proteomics, Cell Metabolism, Agios, Cambridge, MA, USA
contact email	Sebastian.Hayes@Agios.com
lab head
Kate Lizotte
contact affiliation	Agios
contact email	Kate.Lizotte@Agios.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020089
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD020089

PRIDE project URI

Repository Record List

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