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PXD020082

PXD020082 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleMouse (C57BL6/J) osteoblast LC-MS/MS
DescriptionPhysiological pathway of bone metabolism have been characterized well relatively. But antagonic pathway are less well studied. Here we investigated a negative regulator of osteogenesis with peroxiredoxin 5 (Prdx5) knockout mice that shows delay the bone metabolism. Prdx5-deficiency triggers a drastic decrease in both osteoblast and osteoclast number and BMP2 and RANKL level in serum.
HostingRepositoryPRIDE
AnnounceDate2023-02-01
AnnouncementXMLSubmission_2023-01-31_18:46:41.503.xml
DigitalObjectIdentifierhttps://dx.doi.org/10.6019/PXD020082
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportSupported dataset by repository
PrimarySubmitterSang-YeopLee
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListNo PTMs are included in the dataset
InstrumentLTQ Orbitrap Velos
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-29 02:17:52ID requested
12023-01-31 18:46:41announced
Publication List
10.6019/PXD020082;
Keyword List
submitter keyword: mouse, osteoblast, Immunoprecipitation, Prdx5, LC-MS/MS
Contact List
Chang HoonLee
contact affiliationKorea Research Institute of Chemical Technology
contact emaillee2014@krict.re.kr
lab head
Sang-YeopLee
contact affiliationKorea Basic Science Institute
contact emailyopi@kbsi.re.kr
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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