PXD020081 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Phosphorylation level of SIRT1 in proliferating and senescent IMR90 cells |
Description | Mammalian SIRT1 is a central regulator of metabolism and aging. This project is to analyze global phosphorylation levels of mammalian SIRT1 in proliferating and senescence states using human lung fibroblast IMR90, in order to explore the post-translational regulation of SIRT1 protein upon cellular senescence and its potential roles in the regulatory mechanisms of SIRT1 homeostasis. |
HostingRepository | PRIDE |
AnnounceDate | 2020-09-29 |
AnnouncementXML | Submission_2020-09-28_22:30:43.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Congcong Lu |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | phosphorylated residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-29 01:02:30 | ID requested | |
⏵ 1 | 2020-09-28 22:30:43 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: SIRT1, Phosphorylation, Senescence, IMR90 |
Contact List
Benjamin A. Garcia |
contact affiliation | Department of Biochemistry and Biophysics Penn Epigenetics Institute University of Pennsylvania School of Medicine |
contact email | bgarci@pennmedicine.upenn.edu |
lab head | |
Congcong Lu |
contact affiliation | University of Pennsylvania School of Medicine |
contact email | congclu@pennmedicine.upenn.edu |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/09/PXD020081 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD020081
- Label: PRIDE project
- Name: Phosphorylation level of SIRT1 in proliferating and senescent IMR90 cells