PXD019976

PXD019976 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	A research and new understanding for autoimmune sterility from seminal plasma proteomics
Description	The global infertility rate has been increasing annually, and male infertility becoming severe. The proportion of idiopathic infertility is high, with most patients with ambiguous clinical symptoms. These symptoms manifested as declining semen quality, and the effects of autoimmune factors on this measure of fertility cannot be ignored. Aside from anti-sperm antibody for autoimmune infertility, detection indexes for male infertility are lacking. We successfully collected seminal fluid via electric stimulation from an experimental model of autoimmune orchitis in rats. We used the most advanced isobaric tags for relative and absolute quantitative proteomics analysis to analyze the seminal plasma of autoimmune infertility.
HostingRepository	PRIDE
AnnounceDate	2025-05-06
AnnouncementXML	Submission_2025-05-06_07:36:07.649.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Zun pan Fan
SpeciesList	scientific name: Rattus norvegicus (Rat); NCBI TaxID: 10116;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive Plus

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-23 18:14:37	ID requested
⏵ 1	2025-05-06 07:36:08	announced

Publication List

10.4103/aja202389;
Shen QZ, Wang YF, Fang YW, Chen YY, He LT, Zhang Y, Liu GT, Zhao K, Liu CY, Fan ZP, Zhang HP, Seminal plasma S100A8/A9 as a potential biomarker of genital tract inflammation. Asian J Androl, 26(5):464-471(2024) [pubmed]

10.4103/aja202389;

Shen QZ, Wang YF, Fang YW, Chen YY, He LT, Zhang Y, Liu GT, Zhao K, Liu CY, Fan ZP, Zhang HP, Seminal plasma S100A8/A9 as a potential biomarker of genital tract inflammation. Asian J Androl, 26(5):464-471(2024) [pubmed]

Keyword List

submitter keyword: male infertility； orchitis；autoimmunity,；idiopathic；oxidative stress

submitter keyword: male infertility； orchitis；autoimmunity,；idiopathic；oxidative stress

Contact List

Zun pan Fan
contact affiliation	Institute of Reproductive Health, Tong Ji Medical College, Hua Zhong University of Science and Technology, Wuhan, China.
contact email	zunpanfan@hust.edu.cn
lab head
Zun pan Fan
contact affiliation	Institute of Reproductive Health, Tong Ji Medical College, Hua Zhong University of Science and Technology, Wuhan, China.
contact email	zunpanfan@hust.edu.cn
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD019976
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2025/05/PXD019976

PRIDE project URI

Repository Record List

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