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PXD019973

PXD019973 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleThe gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice - Proteomics results
DescriptionIn this study, mice were colonized from birth on with the minimal microbiota Oligo-MM with or without the addition of Extibacter muris. Extibacter muris is known to metabolize cholic acid to deoxycholic acid via 7α-dehydroxylation. The impact of Extibacter muris colonization on the liver proteome of mice under different diets was investigated using untargeted proteomics.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:17:24.096.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterIsabel Karkossa
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListiodoacetamide derivatized residue
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-23 18:13:33ID requested
12021-01-04 07:05:40announced
22024-10-22 05:17:24announced2024-10-22: Updated project metadata.
Publication List
Streidl T, Karkossa I, Segura Mu, ñ, oz RR, Eberl C, Zaufel A, Plagge J, Schmaltz R, Schubert K, Basic M, Schneider KM, Afify M, Trautwein C, Tolba R, Stecher B, Doden HL, Ridlon JM, Ecker J, Moustafa T, von Bergen M, Ramer-Tait AE, Clavel T, produces secondary bile acids and influences liver physiology in gnotobiotic mice. Gut Microbes, 13(1):1-21(2021) [pubmed]
10.1080/19490976.2020.1854008;
Keyword List
submitter keyword: Mouse, TMT, Liver, Extibacter muris
Contact List
Kristin Schubert
contact affiliationDepartment of Molecular Systems Biology, UFZ, Helmholtz-Centre for Environmental Research, Leipzig, Germany
contact emailkristin.schubert@ufz.de
lab head
Isabel Karkossa
contact affiliationHelmholtz-Centre for Environmental Research - UFZ
contact emailisabel.karkossa@ufz.de
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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