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PXD019907

PXD019907 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleOTUD5 complex mass spectrometry
DescriptionDUBs are involved in various pathways and signalling networks by pairing with E3 ubiquitin ligases in protein complexes. In order to test whether OTUD5 associates with an E3 ubiquitin ligase to regulate cell proliferation, the stable Flag-OTUD5/Hep3B cell line was established by transfecting Hep3B cells with plasmids expressing pCIN4-Flag-OTUD5. The cellular factors interacting with OTUD5 were purified by anti-Flag antibody-conjugated M2 beads.
HostingRepositoryPRIDE
AnnounceDate2020-09-11
AnnouncementXMLSubmission_2020-09-11_03:36:02.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterFangzhou Li
SpeciesList scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationListNo PTMs are included in the dataset
InstrumentQ Exactive HF
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-19 08:54:21ID requested
12020-09-11 03:36:03announced
Publication List
Li F, Sun Q, Liu K, Zhang L, Lin N, You K, Liu M, Kon N, Tian F, Mao Z, Li T, Tong T, Qin J, Gu W, Li D, Zhao W, OTUD5 cooperates with TRIM25 in transcriptional regulation and tumor progression via deubiquitination activity. Nat Commun, 11(1):4184(2020) [pubmed]
Keyword List
submitter keyword: OTUD5, protein complex
Contact List
Fangzhou Li
contact affiliationPeking university
contact emailli661219@126.com
lab head
Fangzhou Li
contact affiliationPeking university
contact emailli661219@126.com
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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