PXD019853

PXD019853 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Deep chemoproteomic analysis of LPS-stimulated RAW264.7 cell proteome
Description	Unanticipated regulatory protein modifications can be discovered from the unbiased comprehensive analysis of biological systems using SAMPEI. To explore this idea, we sought to map protein modifications induced during mammalian cell differentiation, modeled by the response of mouse RAW264.7 macrophage cells to lipopolysaccharide (LPS), a potent inducer of macrophage activation and differentiation that involves extensive protein and metabolic signaling.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:24:11.468.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Alex Kentsis
SpeciesList	scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationList	monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-17 15:45:15	ID requested
1	2021-07-22 11:41:22	announced
2	2021-07-22 23:21:51	announced	2021-07-23: Updated project metadata.
⏵ 3	2024-10-22 05:24:13	announced	2024-10-22: Updated project metadata.

Publication List

Cifani P, Li Z, Luo D, Grivainis M, Intlekofer AM, Feny, ö D, Kentsis A, Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. J Proteome Res, 20(4):1835-1848(2021) [pubmed]
10.1021/acs.jproteome.0c00638;

Cifani P, Li Z, Luo D, Grivainis M, Intlekofer AM, Feny, ö D, Kentsis A, Discovery of Protein Modifications Using Differential Tandem Mass Spectrometry Proteomics. J Proteome Res, 20(4):1835-1848(2021) [pubmed]

10.1021/acs.jproteome.0c00638;

Keyword List

submitter keyword: LC-MSMS SAMPEI modifications PTM Orbitrap macrophages LPS SCX

submitter keyword: LC-MSMS SAMPEI modifications PTM Orbitrap macrophages LPS SCX

Contact List

Alex Kentsis
contact affiliation	Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA
contact email	kentsisresearchgroup@gmail.com
lab head
Alex Kentsis
contact affiliation	Memorial Sloan Kettering Cancer Center
contact email	kentsisresearchgroup@gmail.com
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD019853
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/07/PXD019853

PRIDE project URI

Repository Record List

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