PXD019852

PXD019852 is an original dataset announced via ProteomeXchange.

Title	Holistic proteome analyses of heart samples from GHR-deficient (GHR-KO) pigs
Description	A proteomics analysis of heart samples from GH receptor deficient (GHR-KO) pigs has been performed. This animal model is unique to study consequences of lacking GH actions. In this study, we used LC-MS/MS to capture alterations in the heart proteome of this clinically relevant large animal model.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:15:58.280.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Thomas Fröhlich
SpeciesList	scientific name: Sus scrofa domesticus (domestic pig); NCBI TaxID: 9825;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-17 15:43:59	ID requested
1	2020-12-01 08:33:47	announced
⏵ 2	2024-10-22 05:16:02	announced	2024-10-22: Updated project metadata.

Hinrichs A, Riedel EO, Klymiuk N, Blutke A, Kemter E, L, ä, ngin M, Dahlhoff M, Ke, ß, ler B, Kurome M, Zakhartchenko V, Jemiller EM, Ayares D, Bidlingmaier M, Flenkenthaler F, Hrab, ĕ, de Angelis M, Arnold GJ, Reichart B, Fr, ö, hlich T, Wolf E, Growth hormone receptor knockout to reduce the size of donor pigs for preclinical xenotransplantation studies. Xenotransplantation, 28(2):e12664(2021) [pubmed]

10.1111/xen.12664;

submitter keyword: Growth hormone

Laron syndrome

Heart

Pig model

Proteomics

Thomas Fröhlich
contact affiliation	Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany
contact email	frohlich@genzentrum.lmu.de
lab head
Thomas Fröhlich
contact affiliation	Laboratory for Functional Genome Analysis Gene Center Munich Ludwig-Maximilians-Universität Munich (LMU) Feodor-Lynen-Str. 25 81377 Munich Germany
contact email	frohlich@genzentrum.lmu.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/12/PXD019852

PRIDE project URI

• PRIDE
  1. PXD019852
     1. Label: PRIDE project
     2. Name: Holistic proteome analyses of heart samples from GHR-deficient (GHR-KO) pigs