PXD019779 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Proteomic analysis of SYNCRIP deficient HSPCs |
Description | Alterations in SYNCRIP activity were found to alter gene transcription in leukemia cells. The effects of transcription alterations on expression of the corresponding proteins were investigated by LC/MSMS |
HostingRepository | PRIDE |
AnnounceDate | 2024-10-22 |
AnnouncementXML | Submission_2024-10-22_05:45:29.123.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Alex Kentsis |
SpeciesList | scientific name: Mus musculus (Mouse); NCBI TaxID: 10090; |
ModificationList | monohydroxylated residue; iodoacetamide derivatized residue; deamidated residue |
Instrument | Orbitrap Fusion |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-15 03:10:30 | ID requested | |
1 | 2023-05-10 09:09:32 | announced | |
2 | 2023-11-14 08:46:02 | announced | 2023-11-14: Updated project metadata. |
⏵ 3 | 2024-10-22 05:45:31 | announced | 2024-10-22: Updated project metadata. |
Publication List
Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu EL, Joshi S, Barin E, Schurer A, Chan M, Chang K, Han GYQ, Pierson AJ, Xiao M, Yang X, Kuehm LM, Hong Y, Nguyen DTT, Chiosis G, Kentsis A, Leslie C, Vu LP, Kharas MG, RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nat Commun, 14(1):2290(2023) [pubmed] |
10.1038/s41467-023-38001-x; |
Keyword List
submitter keyword: LC-MSMS AML murine SYNCRIP transcription regulation |
Contact List
Alex Kentsis |
contact affiliation | Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA |
contact email | kentsisresearchgroup@gmail.com |
lab head | |
Alex Kentsis |
contact affiliation | Memorial Sloan Kettering Cancer Center |
contact email | kentsisresearchgroup@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2023/05/PXD019779 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019779
- Label: PRIDE project
- Name: Proteomic analysis of SYNCRIP deficient HSPCs