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PXD019779

PXD019779 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleProteomic analysis of SYNCRIP deficient HSPCs
DescriptionAlterations in SYNCRIP activity were found to alter gene transcription in leukemia cells. The effects of transcription alterations on expression of the corresponding proteins were investigated by LC/MSMS
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:45:29.123.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterAlex Kentsis
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListmonohydroxylated residue; iodoacetamide derivatized residue; deamidated residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-15 03:10:30ID requested
12023-05-10 09:09:32announced
22023-11-14 08:46:02announced2023-11-14: Updated project metadata.
32024-10-22 05:45:31announced2024-10-22: Updated project metadata.
Publication List
Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu EL, Joshi S, Barin E, Schurer A, Chan M, Chang K, Han GYQ, Pierson AJ, Xiao M, Yang X, Kuehm LM, Hong Y, Nguyen DTT, Chiosis G, Kentsis A, Leslie C, Vu LP, Kharas MG, RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nat Commun, 14(1):2290(2023) [pubmed]
10.1038/s41467-023-38001-x;
Keyword List
submitter keyword: LC-MSMS AML murine SYNCRIP transcription regulation
Contact List
Alex Kentsis
contact affiliationMolecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA
contact emailkentsisresearchgroup@gmail.com
lab head
Alex Kentsis
contact affiliationMemorial Sloan Kettering Cancer Center
contact emailkentsisresearchgroup@gmail.com
dataset submitter
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Dataset FTP location
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PRIDE project URI
Repository Record List
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