PXD019653 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Cancer tissue classication using machine learning applied to MALDI MSI and high resolution H&E stained images |
Description | To identify a panel of m/z markers for the early detection of colorectal cancer (CRC). Identication of a molecular pattern that can distinguish the primary tumours of colorectal cancer with lymph node metastasis compared to those without. Using MALDI MSI data,we developed and validated a machine learning model that can be used for early screening of CRC. Our model yields high sensitivity and specicity in distinguishing normal tissue from the cancerous. Model described here, can be a used in clinical labs for early diagnosis of colorectal cancer. |
HostingRepository | PRIDE |
AnnounceDate | 2022-02-15 |
AnnouncementXML | Submission_2022-02-15_13:08:30.040.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | Parul Mittal |
SpeciesList | scientific name: Homo sapiens (Human); NCBI TaxID: 9606; |
ModificationList | No PTMs are included in the dataset |
Instrument | ultraflex |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-06-08 07:45:46 | ID requested | |
⏵ 1 | 2022-02-15 13:08:31 | announced | |
Publication List
Mittal P, Condina MR, Klingler-Hoffmann M, Kaur G, Oehler MK, Sieber OM, Palmieri M, Kommoss S, Brucker S, McDonnell MD, Hoffmann P, Cancer Tissue Classification Using Supervised Machine Learning Applied to MALDI Mass Spectrometry Imaging. Cancers (Basel), 13(21):(2021) [pubmed] |
Keyword List
submitter keyword: CRC Colorectal cancer Machine learning MALDI MSI Matrix assisted laser desorption/ionisation mass spectrometry imaging |
Contact List
Prof Peter Hoffmann |
contact affiliation | Strand Leader and Lloyd Sansom Chair Biomaterials Engineering and Nanomedicine Future Industries Institute I Building X – X1-10 Mawson Lakes Campus I GPO Box 2471 |
contact email | peter.hoffmann@unisa.edu.au |
lab head | |
Parul Mittal |
contact affiliation | Research associate |
contact email | pearl106@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/02/PXD019653 |
PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD019653
- Label: PRIDE project
- Name: Cancer tissue classication using machine learning applied to MALDI MSI and high resolution H&E stained images