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PXD019597 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitlePhosphorylation of GABAAR α2 subunit
Descriptionγ-aminobutyric acid type A receptors (GABAARs) mediate fast synaptic inhibition. Phosphorylation governs GABAARs function and trafficking in α4, β and γ subunits. However, phosphorylation of other subunits has not been demonstrated. Here we show that the α2 subunit is phosphorylated on S359.
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterYasuko Nakamura
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListphosphorylated residue
InstrumentLTQ Orbitrap Elite
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-04 22:35:50ID requested
12020-07-03 01:00:07announced
22020-07-07 06:39:33announced2020-07-07: Updated publication reference for PubMed record(s): 32620552.
Publication List
Nakamura Y, Morrow DH, Nathanson AJ, Henley JM, Wilkinson KA, Moss SJ, 2 subunit in GABA type A receptors down-regulates their density at inhibitory synapses. J Biol Chem, 295(35):12330-12342(2020) [pubmed]
Keyword List
submitter keyword: Phosphorylation, GABAAR, α2
Contact List
Stephen James Moss
contact affiliationProfessor of Neuroscience Tufts University USA
contact emailStephen.Moss@tufts.edu
lab head
Yasuko Nakamura
contact affiliationUniversity of Bristol
contact emailanxyn@bristol.ac.uk
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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