PXD019590

PXD019590 is an original dataset announced via ProteomeXchange.

Title	Wobble tRNA modification dependent protein aggregates modification
Description	We want to assess the features of proteins whose aggregation depends on defects in traslation by the loss of the mcm5s2 modification on the urifdine in position 34 of some tRNAs.
HostingRepository	PRIDE
AnnounceDate	2021-02-24
AnnouncementXML	Submission_2021-04-22_22:35:44.101.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD019590
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Dominique Baiwir
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	iodoacetamide derivatized residue
Instrument	Q Exactive

Revision	Datetime	Status	ChangeLog Entry
0	2020-06-04 06:57:23	ID requested
1	2021-02-24 00:09:11	announced
⏵ 2	2021-04-22 22:35:44	announced	2021-04-23: Updated publication reference for PubMed record(s): 33859181.

Rapino F, Zhou Z, Roncero Sanchez AM, Joiret M, Seca C, El Hachem N, Valenti G, Latini S, Shostak K, Geris L, Li P, Huang G, Mazzucchelli G, Baiwir D, Desmet CJ, Chariot A, Georges M, Close P, Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nat Commun, 12(1):2170(2021) [pubmed]

submitter keyword: Cancer, tRNA modification, aggregates, elongator

Pierre CLOSE
contact affiliation	Lab of Cancer Signaling; GIGA-Stem Cell; University of Liege, Belgium
contact email	pierre.close@uliege.be
lab head
Dominique Baiwir
contact affiliation	University of Liege
contact email	D.Baiwir@ulg.ac.be
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD019590

PRIDE project URI

• PRIDE
  1. PXD019590
     1. Label: PRIDE project
     2. Name: Wobble tRNA modification dependent protein aggregates modification