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PXD019528

PXD019528 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleCigarette smoke extract-treated alveolar macrophage-derived extracellular vesicles
DescriptionThis project is based upon the fundamental observation that alveolar macrophage-derived extracellular vesicles (AM-EVs), when internalized by neighboring epithelial cells, inhibit their infection by influenza virus. This inhibitory activity of AM-EVs is abolished when AMs are treated with cigarette smoke extract (CSE). We chose to survey the AM-EV proteome in an effort to identify candidate proteins whose abundance within EVs was downregulated by CSE treatment of AMs, thus explaining the ability of CSE to abrogate the inhibitory activity against influenza.
HostingRepositoryPRIDE
AnnounceDate2024-10-22
AnnouncementXMLSubmission_2024-10-22_05:06:53.126.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterDaniel Schneider
SpeciesList scientific name: Mus musculus (Mouse); NCBI TaxID: 10090;
ModificationListTMT6plex-126 reporter+balance reagent acylated residue
InstrumentOrbitrap Fusion
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-06-02 18:17:59ID requested
12020-06-08 16:58:25announced
22024-10-22 05:06:53announced2024-10-22: Updated project metadata.
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: extracellular vesicle,Alveolar macrophage, cigarette smoke
Contact List
Daniel Joseph Schneider
contact affiliationDepartment of Internal Medicine Division of Pulmonary and Critical Care Medicine, University of Michigan, Ann Arbor, MI, USA
contact emailschneidd@umich.edu
lab head
Daniel Schneider
contact affiliationUniversity of Michigan
contact emailschneidd@med.umich.edu
dataset submitter
Full Dataset Link List
Dataset FTP location
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PRIDE project URI
Repository Record List
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