PXD019458

PXD019458 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Integrated proteomics and phosphoproteomics analyses reveal the broad and complex influence by inhibition of L-type amino acid transporter-1 in biliary tract carcinoma cells
Description	To characterize the changes of phosphorylation signaling cascades and protein expressions induced by LAT1 inhibition in 4 cell lines of biliary tract cancer treated with LAT1 specific inhibitor JPH203, immobilized metal affinity chromatography and liquid chromatography-tandem mass spectrometry with MS2-based quantitation of tandem mass tag were utilized.
HostingRepository	jPOST
AnnounceDate	2020-12-25
AnnouncementXML	Submission_2022-09-18_02:55:38.385.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD019458
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Hiroki
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	S-carboxamidomethyl-L-cysteine; L-methionine sulfoxide; TMT6plex reporter+balance reagent N-acylated residue; TMT6plex reporter+balance reagent acylated N-terminal; O-phospho-L-serine; O-phospho-L-threonine; O4'-phospho-L-tyrosine; deamidated L-glutamine; deamidated L-asparagine
Instrument	Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-28 19:16:56	ID requested
1	2020-12-24 19:51:58	announced
2	2021-02-04 17:24:46	announced	2021-02-04: Updated FTP location.
⏵ 3	2022-09-18 02:55:39	announced	2022-09-18: Updated FTP location.

Publication List

Okanishi H, Ohgaki R, Okuda S, Endou H, Kanai Y, Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor. Cancer Sci, 112(2):871-883(2021) [pubmed]

Okanishi H, Ohgaki R, Okuda S, Endou H, Kanai Y, Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor. Cancer Sci, 112(2):871-883(2021) [pubmed]

Keyword List

submitter keyword: human, LAT1, JPH203, IMAC

submitter keyword: human, LAT1, JPH203, IMAC

Contact List

Yoshikatsu Kanai
lab head
Hiroki
contact affiliation	Okanishi
dataset submitter

Full Dataset Link List

jPOST dataset URI
Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000856/

jPOST dataset URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.jpostdb.org/JPST000856/