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PXD019378

PXD019378 is an original dataset announced via ProteomeXchange.

Dataset Summary
TitleHyposuccinylation Derived from Abnormal Metabolism Promotes the Cell Migration of Esophageal Squamous Cell Cancer
DescriptionWe identify abnormal protein and post-translational modification (PTM) pathways, including many downregulated lysine succinylation sites in cancer cells. Focusing on hyposuccinylation, we reveal that this altered PTM was enriched on enzymes of metabolic pathways and the reduced succinyl-CoA may lead to this phenomenon.
HostingRepositoryiProX
AnnounceDate2020-05-25
AnnouncementXMLSubmission_2020-05-25_15:35:25.xml
DigitalObjectIdentifier
ReviewLevelPeer-reviewed dataset
DatasetOriginOriginal dataset
RepositorySupportUnsupported dataset by repository
PrimarySubmitterZhenchang Guo
SpeciesList scientific name: Homo sapiens; NCBI TaxID: 9606;
ModificationList6x(13)C labeled L-lysine; acetylated residue; phosphorylated residue
InstrumentQ Exactive
Dataset History
RevisionDatetimeStatusChangeLog Entry
02020-05-25 15:33:21ID requested
12020-05-25 15:35:25announced
Publication List
Dataset with its publication pending
Keyword List
submitter keyword: Lysine succinylation, acetylation, phosphorylation, ESCC, proteomics
Contact List
Kai Zhang
contact affiliationDepartment of Biochemistry and Molecular Biology, Tianjin Medical University
contact emailkzhang@tmu.edu.cn
lab head
Zhenchang Guo
contact affiliationTianjin Medical University
contact emailguozhenchang@tmu.edu.cn
dataset submitter
Full Dataset Link List
iProX dataset URI