PXD019314

PXD019314 is an original dataset announced via ProteomeXchange.

Title	The protein repertoires of hydatid fluid from pulmonary cystic echinococcosis
Description	Echinococcosis is a disease resulting from infection by flatworms of the Echinococcus genus. The vast majority of cystic echinococcosis cases in Southern Brazil are caused by Echinococcus granulosus and Echinococcus ortleppi. Here, we surveyed the protein contents of the hydatid fluid compartment of E. granulosus and E. ortleppi pulmonary bovine cysts, in an attempt to compare their molecular arsenal in this host-parasite interface. We detected some molecular players equally in E. granulosus and E. ortleppi, such as proteolytic enzymes and development signaling molecules, while some activities were more evident in one species, such as apoptosis in E. ortleppi, and cysteine protease activity in E. granulosus.
HostingRepository	PRIDE
AnnounceDate	2022-05-25
AnnouncementXML	Submission_2022-05-25_04:40:00.740.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD019314
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Arnaldo Zaha
SpeciesList	scientific name: Echinococcus ortleppi; NCBI TaxID: 446560; scientific name: Echinococcus granulosus; NCBI TaxID: 6210;
ModificationList	Ammonia-loss; Dehydrated; Oxidation; Acetyl; monohydroxylated residue; Carbamidomethyl; iodoacetamide derivatized residue
Instrument	LTQ Orbitrap Velos

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-20 17:23:28	ID requested
⏵ 1	2022-05-25 04:40:01	announced

Dos Santos GB, da Silva ED, Kitano ES, Battistella ME, Monteiro KM, de Lima JC, Ferreira HB, Serrano SMT, Zaha A, Proteomic profiling of hydatid fluid from pulmonary cystic echinococcosis. Parasit Vectors, 15(1):99(2022) [pubmed]

submitter keyword: Echinococcus granulosus, Echinococcus ortleppi, hydatid fluid, host-parasite interface

Arnaldo Zaha
contact affiliation	Laboratório de Biologia Molecular de Cestódeos, Centro de Biotecnologia, Universidade Federal do Rio Grande Do Sul, Porto Alegre, Brazil
contact email	zaha@cbiot.ufrgs.br
lab head
Arnaldo Zaha
contact affiliation	Laboratório de Biologia Molecular de Cestódeos, Centro de Biotecnologia, Universidade Federal do Rio Grande do Sul
contact email	zaha@cbiot.ufrgs.br
dataset submitter

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PRIDE project URI

• PRIDE
  1. PXD019314
     1. Label: PRIDE project
     2. Name: The protein repertoires of hydatid fluid from pulmonary cystic echinococcosis