PXD019236
PXD019236 is an original dataset announced via ProteomeXchange.
Dataset Summary
| Title | Global protein data of proteomics of spleen infected by Babesia microti |
| Description | Babesia is a kind of protozoa parasitic in the red blood cells of some vertebrates. Some species of Babesia can cause human and animal co-infection and do great harm. As the largest immune organ in mammals, spleen plays an important role in resisting Babesia infection. Although the spleen infected by Babesia is seriously damaged, it still initiates the immunomodulatory response actively. In order to further explore the molecular mechanism of immune regulation and self-repair of spleen in response to infection, DIA quantitative proteomics was used to analyze the changes of total protein expression and phosphorylation modification in spleen tissue of mice infected with Babesia microti, so as to explore the self-regulation mechanism of spleen in the process of injury and repair. It provides an important basis for the diagnosis and treatment of babesiosis. |
| HostingRepository | iProX |
| AnnounceDate | 2020-05-16 |
| AnnouncementXML | Submission_2023-03-01_18:26:17.996.xml |
| DigitalObjectIdentifier | |
| ReviewLevel | Peer-reviewed dataset |
| DatasetOrigin | Original dataset |
| RepositorySupport | Unsupported dataset by repository |
| PrimarySubmitter | Xiaomin Xue |
| SpeciesList | scientific name: Babesia microti; NCBI TaxID: 5868; |
| ModificationList | No PTMs are included in the dataset |
| Instrument | Q Exactive HF |
Dataset History
| Revision | Datetime | Status | ChangeLog Entry |
|---|---|---|---|
| 0 | 2020-05-17 07:14:50 | ID requested | |
| 1 | 2020-05-17 07:16:33 | announced | |
| ⏵ 2 | 2023-03-01 18:26:20 | announced | 2023-03-02: Update publication information. |
Publication List
| Xue X, Ren S, Yang X, Masoudi A, Hu Y, Wang X, Li H, Zhang X, Wang M, Wang H, Liu J, Protein regulation strategies of the mouse spleen in response to Babesia microti infection. Parasit Vectors, 14(1):61(2021) [pubmed] |
Keyword List
| submitter keyword: Babesia microti, spleen, phosphorylation, quantitative proteomics, immunity |
Contact List
| Jingze Liu | |
|---|---|
| contact affiliation | Hebei normal University |
| contact email | liujingze@hebtu.edu.cn |
| lab head | |
| Xiaomin Xue | |
| contact affiliation | Hebei normal University |
| contact email | 1099909169@qq.com |
| dataset submitter | |
Full Dataset Link List
| iProX dataset URI |
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