PXD019193

PXD019193 is an original dataset announced via ProteomeXchange.

Title	quantitative proteomic analysis of proteasome in response to MG132
Description	The ubiquitin-proteasome system and autophagy are two major intracellular proteolytic pathways and both remove misfolded and proteotoxic proteins from eukaryotic cells. This study describes the detailed informations about the change in composition and interactome of proteasomes after prolonged MG132 treatment.
HostingRepository	PRIDE
AnnounceDate	2021-09-09
AnnouncementXML	Submission_2021-09-08_19:22:56.756.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Dohyun Han
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	ubiquitination signature dipeptidyl lysine; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive Plus

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-14 05:24:15	ID requested
⏵ 1	2021-09-08 19:22:57	announced

Choi WH, Yun Y, Park S, Jeon JH, Lee J, Lee JH, Yang SA, Kim NK, Jung CH, Kwon YT, Han D, Lim SM, Lee MJ, Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes. Proc Natl Acad Sci U S A, 117(32):19190-19200(2020) [pubmed]

submitter keyword: proteasome, interactome, MG132

Dohyun Han
contact affiliation	Proteomics core facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
lab head
Dohyun Han
contact affiliation	Proteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital
contact email	hdh03@snu.ac.kr
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/09/PXD019193

PRIDE project URI

• PRIDE
  1. PXD019193
     1. Label: PRIDE project
     2. Name: quantitative proteomic analysis of proteasome in response to MG132