PXD019082

PXD019082 is an original dataset announced via ProteomeXchange.

Title	A2M Q975C and C3 Q1013C disulfide mutants
Description	Mutant A2M and C3 with disulfides replacing their thiol esters were disulfide mapped via pepsin digests.
HostingRepository	PRIDE
AnnounceDate	2021-02-18
AnnouncementXML	Submission_2021-02-18_00:36:26.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Seandean Harwood
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	No PTMs are included in the dataset
Instrument	Orbitrap Eclipse

Revision	Datetime	Status	ChangeLog Entry
0	2020-05-11 07:50:51	ID requested
1	2021-02-18 00:15:09	announced
⏵ 2	2021-02-18 00:36:27	announced	2021-02-18: Updated project metadata.

10.1021/ACS.BIOCHEM.0C00803;

Harwood SL, Nielsen NS, Pedersen H, Kj, ø, ge K, Nielsen PK, Andersen GR, Enghild JJ, Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes. Biochemistry, 59(51):4799-4809(2020) [pubmed]

submitter keyword: Human C3 A2M

Jan J. Enghild
contact affiliation	MBG, Aarhus University, Denmark
contact email	jje@mbg.au.dk
lab head
Seandean Harwood
contact affiliation	Aarhus University
contact email	seandeanlykkeharwood@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/02/PXD019082

PRIDE project URI

• PRIDE
  1. PXD019082
     1. Label: PRIDE project
     2. Name: A2M Q975C and C3 Q1013C disulfide mutants