PXD018940 is an
original dataset announced via ProteomeXchange.
Dataset Summary
Title | Effect of HDAC inhibitors on acetylated histones in P. pacificus |
Description | Western Blot showed that epigenetic control of the mouth dimorphism in P. pacificus correlates with histone 4 acetylation. This result was validated by mass spectrometry. This experiment profiled histone acetylation in the presence and absence of the histone deacetylase (HDAC) inhibitor Trichostatin A (TSA). Histone acetylation was also examined in the presence of another HDAC inhibitor (Na-butyrate), which served as an additional negative control because unlike TSA, it did not induce a phenotypic change. |
HostingRepository | PRIDE |
AnnounceDate | 2023-02-24 |
AnnouncementXML | Submission_2023-02-24_00:35:41.611.xml |
DigitalObjectIdentifier | |
ReviewLevel | Peer-reviewed dataset |
DatasetOrigin | Original dataset |
RepositorySupport | Unsupported dataset by repository |
PrimarySubmitter | NicolasNalpas |
SpeciesList | scientific name: Pristionchus pacificus; NCBI TaxID: 54126; |
ModificationList | No PTMs are included in the dataset |
Instrument | Q Exactive HF-X |
Dataset History
Revision | Datetime | Status | ChangeLog Entry |
0 | 2020-04-30 16:45:16 | ID requested | |
⏵ 1 | 2023-02-24 00:35:41 | announced | |
Publication List
Dataset with its publication pending |
Keyword List
submitter keyword: phenotypic plasticity, epigenetics, histones,Pristionchus pacificus |
Contact List
Ralf J.Sommer |
contact affiliation | Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, 72076 Tübingen |
contact email | ralf.sommer@teubingen.mpg.de |
lab head | |
NicolasNalpas |
contact affiliation | Tuebingen University |
contact email | nalpas.nicolas@gmail.com |
dataset submitter | |
Full Dataset Link List
Dataset FTP location
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PRIDE project URI |
Repository Record List
[ + ]
[ - ]
- PRIDE
- PXD018940
- Label: PRIDE project
- Name: Effect of HDAC inhibitors on acetylated histones in P. pacificus