PXD018926

PXD018926 is an original dataset announced via ProteomeXchange.

Title	RNF41 regulation of the dendritic cell receptor Clec9A
Description	The dendritic cell receptor Clec9A facilitates processing of dead cell-derived antigens for cross-presentation and the induction of effective CD8+ T cell immune responses. This study investigates the role of E3 ubiquitin ligase RNF41 in Clec9A-mediated ubiquitination, and Clec9A-interactions.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:15:44.753.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Ralf Schittenhelm
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	monohydroxylated residue; acetylated residue; iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-30 00:55:22	ID requested
1	2020-11-26 23:00:38	announced
2	2020-12-08 12:13:19	announced	2020-12-08: Updated publication reference for PubMed record(s): 33264090.
⏵ 3	2024-10-22 05:15:47	announced	2024-10-22: Updated project metadata.

Tullett KM, Tan PS, Park HY, Schittenhelm RB, Michael N, Li R, Policheni AN, Gruber E, Huang C, Fulcher AJ, Danne JC, Czabotar PE, Wakim LM, Mintern JD, Ramm G, Radford KJ, Caminschi I, O'Keeffe M, Villadangos JA, Wright MD, Blewitt ME, Heath WR, Shortman K, Purcell AW, Nicola NA, Zhang JG, Lahoud MH, RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells. Elife, 9():(2020) [pubmed]

10.7554/elife.63452;

submitter keyword: RNF41, E3 ubiquitin ligase, ubiquitination,Clec9A

Mireille Lahoud
contact affiliation	Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Australia
contact email	mireille.lahoud@monash.edu
lab head
Ralf Schittenhelm
contact affiliation	Monash University
contact email	ralf.schittenhelm@monash.edu
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2020/11/PXD018926

PRIDE project URI

• PRIDE
  1. PXD018926
     1. Label: PRIDE project
     2. Name: RNF41 regulation of the dendritic cell receptor Clec9A