PXD018782

PXD018782 is an original dataset announced via ProteomeXchange.

Dataset Summary

Title	Phosphoproteomic analysis in Glioblastoma in response to AZD1775
Description	The aim of this study was to characterize phosphoproteome in response to AZD1775 in patient derived xenografts (PDX) lines and clinical specimens in glioblastoma. Tyrosine and motif specific serine and threonine phosphorylation were measured using quantitative LC-MS/MS based on TMT labeling.
HostingRepository	PRIDE
AnnounceDate	2023-11-14
AnnouncementXML	Submission_2023-11-14_07:52:33.049.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD018782
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Ishwar Kohale
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	TMT6plex-126 reporter+balance reagent acylated residue; Phospho; TMT6plex; phosphorylated residue; Oxidation; Carbamidomethyl; monohydroxylated residue; iodoacetamide derivatized residue
Instrument	Q Exactive HF; Q Exactive

Dataset History

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-24 01:28:38	ID requested
1	2022-10-13 08:07:13	announced
⏵ 2	2023-11-14 07:52:33	announced	2023-11-14: Updated project metadata.

Publication List

Lopez BGC, Kohale IN, Du Z, Korsunsky I, Abdelmoula WM, Dai Y, Stopka SA, Gaglia G, Randall EC, Regan MS, Basu SS, Clark AR, Marin BM, Mladek AC, Burgenske DM, Agar JN, Supko JG, Grossman SA, Nabors LB, Raychaudhuri S, Ligon KL, Wen PY, Alexander B, Lee EQ, Santagata S, Sarkaria J, White FM, Agar NYR, Multimodal platform for assessing drug distribution and response in clinical trials. Neuro Oncol, 24(1):64-77(2022) [pubmed]
10.6019/PXD018782;

Lopez BGC, Kohale IN, Du Z, Korsunsky I, Abdelmoula WM, Dai Y, Stopka SA, Gaglia G, Randall EC, Regan MS, Basu SS, Clark AR, Marin BM, Mladek AC, Burgenske DM, Agar JN, Supko JG, Grossman SA, Nabors LB, Raychaudhuri S, Ligon KL, Wen PY, Alexander B, Lee EQ, Santagata S, Sarkaria J, White FM, Agar NYR, Multimodal platform for assessing drug distribution and response in clinical trials. Neuro Oncol, 24(1):64-77(2022) [pubmed]

10.6019/PXD018782;

Keyword List

submitter keyword: Phosphoproteomics,AZD1775, Glioblastoma

submitter keyword: Phosphoproteomics,AZD1775, Glioblastoma

Contact List

Forest Michael White
contact affiliation	Department of Biological Engineering, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States
contact email	fwhite@mit.edu
lab head
Ishwar Kohale
contact affiliation	Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA
contact email	ikohale@mit.edu
dataset submitter

Full Dataset Link List

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD018782
PRIDE project URI

Dataset FTP location
NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/10/PXD018782

PRIDE project URI

Repository Record List

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