PXD018635

PXD018635 is an original dataset announced via ProteomeXchange.

Title	Drosophila nephrocytes Bazooka knockdown vs control
Description	We assessed the functional role of the cell polarity protein Bazooka on nephrocyte function. Here, we did a proteomics anaylsis of isolated garland nephrocytes from 3rd install larvae. Analysis of the data identified several differentially regulated proteins.
HostingRepository	PRIDE
AnnounceDate	2024-10-22
AnnouncementXML	Submission_2024-10-22_05:38:07.111.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Martin Hoehne
SpeciesList	scientific name: Drosophila melanogaster (Fruit fly); NCBI TaxID: 7227;
ModificationList	No PTMs are included in the dataset
Instrument	Q Exactive HF

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-18 15:30:07	ID requested
1	2022-07-07 09:11:23	announced
⏵ 2	2024-10-22 05:38:07	announced	2024-10-22: Updated project metadata.

10.1016/j.kint.2021.11.030;

Koehler S, Odenthal J, Ludwig V, Unnersj, ö, Jess D, H, ö, hne M, J, ü, ngst C, Grawe F, Helmst, ä, dter M, Janku JL, Bergmann C, Hoyer PF, Hagmann HH, Walz G, Bloch W, Niessen C, Schermer B, Wodarz A, Denholm B, Benzing T, Iden S, Brinkkoetter PT, Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney Int, 101(4):733-751(2022) [pubmed]

submitter keyword: nephrocyte, Bazooka,Drosophila

Paul Thomas Brinkkoetter
contact affiliation	Klinik II für Innere Medizin: Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin Zentrum für Molekulare Medizin Köln (ZMMK) Uniklinik Köln Kerpener Str. 62 D-50937 Köln
contact email	paul.brinkkoetter@uk-koeln.de
lab head
Martin Hoehne
contact affiliation	1) Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany 2) CECAD, University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany
contact email	martin.hoehne@uk-koeln.de
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/07/PXD018635

PRIDE project URI

• PRIDE
  1. PXD018635
     1. Label: PRIDE project
     2. Name: Drosophila nephrocytes Bazooka knockdown vs control