PXD018602

PXD018602 is an original dataset announced via ProteomeXchange.

Title	Identification of barrier-specific proteins in the human brain
Description	We present a proteomic analysis of the basal lamina of the human BBB. We combined laser capture microdissection with shotgun proteomics for selective enrichment and identification of specific proteins present in the cerebral microvasculature and arachnoidal vessels collected from normal human brain tissue specimens. Proteins found to be barrier-specific were validated by immunohistochemistry.
HostingRepository	PRIDE
AnnounceDate	2022-01-17
AnnouncementXML	Submission_2022-01-24_02:19:15.618.xml
DigitalObjectIdentifier	https://dx.doi.org/10.6019/PXD018602
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Supported dataset by repository
PrimarySubmitter	Marina Zajec
SpeciesList	scientific name: Homo sapiens (Human); NCBI TaxID: 9606;
ModificationList	Oxidation; Carbamidomethyl
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-16 06:21:25	ID requested
1	2022-01-17 01:33:04	announced
⏵ 2	2022-01-24 02:19:16	announced	2022-01-24: Updated publication reference for PubMed record(s): 33226812.

Zajec M, Kros JM, Dekker-Nijholt DAT, Dekker LJ, Stingl C, van der Weiden M, van den Bosch TPP, Mustafa DAM, Luider TM, Identification of Blood-Brain Barrier-Associated Proteins in the Human Brain. J Proteome Res, 20(1):531-537(2021) [pubmed]

submitter keyword: blood-brain barrier, proteomics, mass spectrometry

Theo Luider
contact affiliation	Department of Neurology, Erasmus MC
contact email	t.luider@erasmusmc.nl
lab head
Marina Zajec
contact affiliation	Erasmus MC
contact email	m.zajec@erasmusmc.nl
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2022/01/PXD018602

PRIDE project URI

• PRIDE
  1. PXD018602
     1. Label: PRIDE project
     2. Name: Identification of barrier-specific proteins in the human brain