PXD018599

PXD018599 is an original dataset announced via ProteomeXchange.

Title	Sphingobium indicum B90A nLC-MS/MS
Description	The project aims to to understand the response of the lin genes in Sphingobium indicum B90A under the stress of HCH isomers and the metabolites formed during degradation of hexachlorocyclohexane (HCH). Entire cell proteome from Sphingobium indicum B90A was extracted in presence of four HCH isomers. Quantitative proteomics confirmed the constitutive expression of the linA, linB and linC genes of the HCH degradation pathway crucial for the initiation of HCH isomers degradation. LinM and LinN were upregulated in the presence of β- and δ-isomers suggested the important role of ABC transporter system in the depletion of β- and δ-HCH. Besides this HCH isomers induced oxidative stress caused systemic changes in strain B90A proteome.
HostingRepository	PRIDE
AnnounceDate	2021-04-06
AnnouncementXML	Submission_2021-04-05_23:10:05.898.xml
DigitalObjectIdentifier
ReviewLevel	Peer-reviewed dataset
DatasetOrigin	Original dataset
RepositorySupport	Unsupported dataset by repository
PrimarySubmitter	Rup Lal
SpeciesList	scientific name: Sphingobium indicum B90A; NCBI TaxID: 861109;
ModificationList	iodoacetamide derivatized residue
Instrument	Orbitrap Fusion

Revision	Datetime	Status	ChangeLog Entry
0	2020-04-16 05:33:45	ID requested
⏵ 1	2021-04-05 23:10:07	announced

Sharma M, Singh DN, Budhraja R, Sood U, Rawat CD, Adrian L, Richnow HH, Singh Y, Negi RK, Lal R, Comparative proteomics unravelled the hexachlorocyclohexane (HCH) isomers specific responses in an archetypical HCH degrading bacterium Sphingobium indicum B90A. Environ Sci Pollut Res Int, 28(30):41380-41395(2021) [pubmed]

submitter keyword: Sphingobium indicum B90A, Hexacholorocyclohexane, proteome, nLC-MS/MS, stress response

Rup Lal
contact affiliation	The Energy and Resources Institute Darbari Seth Block, IHC Complex, Lodhi Road New Delhi-110003, India.
contact email	ruplal@gmail.com
lab head
Rup Lal
contact affiliation	The energy and resources institute
contact email	ruplal@gmail.com
dataset submitter

Dataset FTP location NOTE: Most web browsers have now discontinued native support for FTP access within the browser window. But you can usually install another FTP app (we recommend FileZilla) and configure your browser to launch the external application when you click on this FTP link. Or otherwise, launch an app that supports FTP (like FileZilla) and use this address: ftp://ftp.pride.ebi.ac.uk/pride/data/archive/2021/04/PXD018599

PRIDE project URI

• PRIDE
  1. PXD018599
     1. Label: PRIDE project
     2. Name: Sphingobium indicum B90A nLC-MS/MS